The cytosolic GSTs are profusely present and have been divided into divergent classes based on their genesis, catalytic amino-acid residue, sequence similarity, and substrate specificity (Labrou et al., 2015)
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Astragalus IV has also been shown to be able to reshape TME and correct CAFs dysfunction caused by dysregulation of mic RNA expression, thereby inhibiting GC cell proliferation, invasion, and migration (94)